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July 4, 2001

Prenatal Cocaine Exposure as a Risk Factor for Later Developmental Outcomes

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor

JAMA. 2001;286(1):45-47. doi:10.1001/jama.286.1.45

To the Editor: The meta-analysis by Dr Frank and colleagues1 concluded that cocaine exposure in utero does not affect physical or behavioral development in offspring. As pointed out by the authors, many inconsistent observations have been reported in the clinical literature, and confounding factors, such as polydrug use, further complicate the interpretation of these studies.

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