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July 4, 2001

Prenatal Cocaine Exposure as a Risk Factor for Later Developmental Outcomes

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor

JAMA. 2001;286(1):45-47. doi:10.1001/jama.286.17.2162

To the Editor: In their analysis of a large and contradictory literature on the developmental effects of prenatal cocaine exposure, Dr Frank and colleagues1 concluded that, "After controlling for confounders, there was no consistent negative association between prenatal cocaine exposure . . . " and a number of developmental outcomes. Although the authors carefully qualified that they were assessing unique effects of cocaine in comparison with those of multiple other risk factors, one concern is that this review will be interpreted as indicating that there are no negative effects of prenatal cocaine exposure.

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