Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor
Copyright 2001 American Medical Association. All Rights Reserved.
Applicable FARS/DFARS Restrictions Apply to Government Use.2001
To the Editor: A recent Medical News and Perspectives
story reports that the global effort to eradicate poliovirus is 99% complete.1 However, attention recently has been drawn to potential
problems with global eradication,2 including
reintroduction of wild virus into a country free of circulating wild virus,
reversion of the vaccine strain to a more neurotropic form of the virus and
subsequent infection with this reverted strain, persistence of the virus in
the environment, and failure to maintain adequate immunization levels.
Kelly H, Prasopa-Plaizier N, Ballard S. Laboratory Containment of Wild Poliovirus. JAMA. 2001;286(5):536. doi:10.1001/jama.286.5.536-a