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August 22/29, 2001

Chronic Fatigue Syndrome and Posttraumatic Stress Disorder

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor


Copyright 2001 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2001

JAMA. 2001;286(8):916-917. doi:10.1001/jama.286.8.916

To the Editor: In his Contempo Updates article about chronic fatigue syndrome (CFS), Dr Natelson1 did not discuss the relationship between CFS and posttraumatic stress disorder (PTSD). The 2 diagnoses share many features, including fatigue, hypocortisolism,2,3 abnormalities of immune function,4 unrefreshing restless sleep, fluctuations in concentration or memory, headaches, muscle pain, joint pain, and withdrawal from occupational, educational, and social activities.5,6

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