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September 26, 2001

Relationship Between Apolipoprotein E ∊4 and Sleep-Disordered Breathing at Different Ages

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor


Copyright 2001 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2001

JAMA. 2001;286(12):1447-1448. doi:10.1001/jama.286.12.1447

To the Editor: Dr Kadotani and colleagues1 reported an association between apolipoprotein E ∊4 (which is coded by the ApoE4 allele) and sleep-disordered breathing (SDB) in a study of 791 adults, aged 32 to 68 years, in Wisconsin. We examined this association among 718 Japanese-American men, aged 79 to 97 years, who were evaluated for SDB as part of a recent follow-up examination of participants in the Honolulu-Asia Aging Study of dementia that began in 1991 (previously unpublished data).

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