Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor
In Reply: The goal of our study was to determine
the long-term outcome for patients who had participated in a randomized trial
of medical and surgical therapies for GERD in the 1980s. Except for the data
collected on mortality and on invasive procedures performed for the treatment
of GERD since the original trial, the follow-up study involved clinical tests
and questionnaires administered at 1 point, some 10 to 13 years after randomization.
On the basis of those results, Dr Harary is correct that one cannot make valid
conclusions regarding differences between the treatment groups prior to the
conduct of the follow-up study. However, we made no such conclusions anywhere
in our article.
Spechler SJ. Medical vs Surgical Treatment of Gastroesophageal Reflux—Reply. JAMA. 2001;286(14):1709-1712. doi:10.1001/jama.286.14.1709