Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor
Copyright 2001 American Medical Association. All Rights Reserved.
Applicable FARS/DFARS Restrictions Apply to Government Use.2001
In Reply: Since our letter was published, we
have observed 10 additional patients with anemia, reticulocytopenia, and increasing
iron saturation. These patients ranged in age from 24 to 81 years (7 women,
3 men), and all received linezolid (600 mg twice per day) for at least 2 weeks.
Some of these patients were taking several medications and others received
only linezolid. In all cases, the iron saturation and reticulocyte count returned
to normal when linezolid was discontinued. Dr Abena and colleagues observed
this same effect in their patient with sideroblastic anemia while receiving
Green SL, Maddox JC. Linezolid and Reversible Myelosuppression—Reply. JAMA. 2001;286(16):1973-1974. doi:10.1001/jama.286.16.1969