Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor
To the Editor: Dr van Nieuwenhoven and colleagues1 attempted to assess the relationship between trial
quality and estimates of treatment for selective digestive decontamination
(SDD) of critically ill patients.
Despite their claims about the importance of using rigorous methods
of assessment, however, the authors fall short of this standard in several
aspects of their analysis, including identification of studies, choice of
the instrument for assessing trial quality, and presentation and interpretation
of the results.
Liberati A, D'Amico R, Brazzi L, Pifferi S. Influence of Methodological Quality on Study Conclusions. JAMA. 2001;286(20):2544-2547. doi:10.1001/jama.286.20.2542