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December 26, 2001

Salmeterol and Inhaled Corticosteroids in Patients With Persistent Asthma

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor

JAMA. 2001;286(24):3075-3078. doi:10.1001/jama.286.24.3075

To the Editor: Nearly all of the patients in the trial by Dr Lazarus and colleagues1 were previously receiving controller therapy with ICs. In addition to the fact that one third of the trial participants were randomized to placebo for 16 weeks, all participants entered a 6-week "placebo runout" phase at the conclusion of the trial in which controller therapy was withdrawn or withheld.

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