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December 26, 2001

Salmeterol and Inhaled Corticosteroids in Patients With Persistent Asthma

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor

JAMA. 2001;286(24):3075-3078. doi:10.1001/jama.286.24.3075

To the Editor: Dr Lemanske and colleagues1 found that the dosage of IC could be decreased in some patients with persistent asthma who were treated with salmeterol, but that salmeterol was not effective as monotherapy. Like the trial of Dr Lazarus and colleagues,2 this was funded by the National Institutes of Health and included patients between the ages of 12 and 65 years, reflecting the new policy to encourage the participation of children in research.3 This policy was designed to address the concerns that, physiologically, children are not small adults and that many therapies used in pediatrics have never been adequately tested in children.

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