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January 2, 2002

Autologous Transplantation of Whole Ovaries vs Ovarian Cortical Strips

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthorJody W.ZylkeMD, Contributing EditorIndividualAuthor

JAMA. 2002;287(1):44-45. doi:10.1001/jama.287.1.40

To the Editor: Dr Oktay and colleagues1 performed ovarian autotransplantation in the forearm in 2 young women before pelvic irradiation or surgery with the aim of preserving endocrine function. The success of the procedure was assessed by hormonal and ultrasonographic monitoring, during a relatively short follow-up.

In their discussion, the authors present their work as "the first report of endocrine function and oocyte retrieval after autologous grafting of ovarian cortical strips to the forearm." This statement is incorrect: 16 years ago, we performed heterotopic ovarian autotransplantation in the arm of a 15-year-old girl before radiation therapy for pelvic Hodgkin disease. This technique was published after 2 years of follow-up to ensure both hormonal and ovulation functional long-term outcome.2

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