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January 16, 2002

Muscle Protein Synthesis in Younger and Older Men

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthor

JAMA. 2002;287(3):317-318. doi:10.1001/jama.287.3.313

To The Editor: Dr Volpi and colleagues1 found that differences in basal muscle protein turnover in older and younger men do not explain age-related sarcopenia. This conclusion contradicts our collective results, which have found age-related differences in muscle protein synthesis.25 We suggest several reasons for these differences.

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