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February 13, 2002

Sequential Assessment of Multiple Organ Dysfunction as a Predictor of Outcome

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthor

JAMA. 2002;287(6):713-714. doi:10.1001/jama.287.6.711

To the Editor: Dr Ferreira and colleagues1 concluded that sequential assessment of multiple organ dysfunction (MOD) is a good predictor of mortality in critically ill patients, with the highest and the mean Sequential Organ Failure Assessment (SOFA) scores being particularly prognostic. However, their study raises some questions about the definition of mortality, possible factors causing bias, and interpretation of Δ-SOFA (differences between subsequent scores) results.

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