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March 6, 2002

Identifying Fracture Risk in Postmenopausal Women

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthor

JAMA. 2002;287(9):1109-1110. doi:10.1001/jama.287.9.1109

To the Editor: Dr Siris and colleagues1 found an unexpectedly high prevalence of previously undetected low BMD among postmenopausal women. Their study also confirmed the association of well-accepted risk factors including tobacco, glucocorticoids, and family history of osteoporosis, with low BMD.

Although low body weight is mentioned as an associated risk factor, the authors did not discuss anorexia nervosa. Indeed, the association of anorexia nervosa and osteoporosis is important because more than 50% of young patients with anorexia have osteoporosis,2 as well as other medical complications.3 While many of these medical complications are reversed by timely restoration of body weight, osteoporosis may persist even after weight restoration.4

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