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April 10, 2002

Acupuncture for the Treatment of Cocaine Addiction

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthor

JAMA. 2002;287(14):1800-1802. doi:10.1001/jama.287.14.1799

To the Editor: Dr Margolin and colleagues1 report that "acupuncture was not more effective than a needle insertion or relaxation control in reducing cocaine use." In a previous report of these data,2 however, these authors concluded that "findings from the current study suggest that acupuncture shows promises for the treatment of cocaine dependence." The designs of both studies are similar, but the results are opposite. The only difference appears to be a much larger number of patients (620 vs 82) in the more recent study. Does that mean that the release of the earlier report was premature? Should the investigators have waited until they enrolled more patients?

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