April 24, 2002

Effect of High-Dose Amoxicillin on the Prevalence of Penicillin-Resistant Streptococcus pneumoniae in Rural Alaska

Author Affiliations

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthor


Copyright 2002 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2002

JAMA. 2002;287(16):2078-2079. doi:10.1001/jama.287.16.2073

To the Editor: Schrag et al1 recently found that short-course, high-dose amoxicillin therapy could decrease the rate of carriage of penicillin-nonsusceptible Streptococcus pneumoniae (PNSP) 28 days after treatment. We sought to determine whether an increased dosage of amoxicillin for treatment of children can reduce community-wide carriage of PNSP in a remote rural area.

First Page Preview View Large
First page PDF preview
First page PDF preview