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Letters
May 8, 2002

Prevalence of Untreated Sexually Transmitted Disease—Reply

JAMA. 2002;287(18):2362-2363. doi:10.1001/jama.287.18.2359

In Reply: Dr Bush and Dr Handsfield are both concerned about the generalizability of our results. We offer 4 observations in response.

First, our stratified probability sample was designed to be representative of English-speaking adults aged 18 to 35 years in Baltimore, Md. We oversampled segments of the population with higher rates of sexually transmitted diseases (STDs) (ie, young black men, whites living in census tracts with high rates of reported STDs). Oversampling is routinely used in household surveys to ensure adequate sample sizes for difficult-to-survey or numerically rare segments of the population.1,2 The resulting prevalence estimates are not biased by the oversampling and remain generalizable to English-speaking Baltimore adults aged 18 to 35 years because sample weights account for the oversampling in the statistical analysis. Our population-based sample provides one of the first estimations of the prevalence of gonococcal and chlamydial infection in a general population.

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