Stephen J.LurieMD, PhD, Senior EditorIndividualAuthor
To the Editor: Dr Barsky and colleagues1 observe that patients who somatize or who are anxious
or depressed have better recollection of side effects to antidepressant therapy.
While I agree with this observation, there is little support for their suggestion
of a collaborative strategy to treat anxious, depressed, or somatizing patients.
Depressed patients with elevated anxiety and somatic symptoms receiving usual
care for depression have been found to adhere well to antidepressant therapy,
and their anxiety and somatization improve with treatment of depression.2,3
Keeley R. When Are Medication Side Effects Due to the Nocebo Phenomenon?. JAMA. 2002;287(19):2502-2504. doi:10.1001/jama.287.19.2502