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Letters
July 24/31, 2002

St John's Wort and Depression—Reply

Author Affiliations
 

Stephen J.LurieMD, PhD, Senior EditorIndividualAuthor

JAMA. 2002;288(4):446-449. doi:10.1001/jama.288.4.446

In Reply: In response to Dr Jonas, we believe that the design of the trial by Davidson et al1 represents the potentially correct strategy to answer the question concerning hypericum's efficacy. However, the actual results have led to profound skepticism about the design. The major lesson of this study, as reflected by Jonas, is the need to pay better attention to several concerns.

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