Stephen J.LurieMD, PhD, Senior EditorIndividualAuthor
Copyright 2002 American Medical Association. All Rights Reserved.
Applicable FARS/DFARS Restrictions Apply to Government Use.2002
To the Editor: Dr Ludwig reviewed the glycemic
index and its possible role in the establishment and maintenance of insulin
resistance.1 However, in the section addressing
the mechanisms by which a high–glycemic index diet may precipitate cardiovascular
disease, he did not address the cardiovascular effects of counterregulatory
hormones and fatty acids. Such substances may be related to chronically increased
autonomic tone,2 which has many of the same
long-term consequences as insulin resistance.
Brotman DJ. Effects of Counterregulatory Hormones in a High–Glycemic Index Diet. JAMA. 2002;288(6):695. doi:10.1001/jama.288.6.693