Stephen J.LurieMD, PhD, Senior EditorIndividualAuthor
In Reply: Dr Rowe notes that we incorporated
measures of mineral metabolism in our investigation. Although one of our a
priori assumptions was that calcium, phosphorus, and possibly PTH levels would
correlate with pulse pressure, the strength of these associations was weak.
In the multivariable model of pulse pressure, the association of phosphorus
concentrations had a low χ2 value, calcium levels were not
significantly related after adjustment for multiple comparisons, and PTH levels
were not significantly associated.
Klassen PS, Coladonato JA, Reddan DN, Szczech LA, Owen WF. Mineral Metabolism and Vascular Disease in Patients With End-Stage Renal Failure—Reply. JAMA. 2002;288(6):695-696. doi:10.1001/jama.288.6.693