Author Affiliation: Dr Chang (email@example.com) and Dr Zuccotti are both Contributing Editors, JAMA. Dr Zuccotti is also with Partners Healthcare, Boston, Massachusetts.
A 47-year-old Brazilian woman presented to a walk-in clinic reporting a headache of 8 days' duration that started in the frontal area and evolved into a holocranial headache. The intensity progressively worsened, and she developed vomiting 2 days earlier. She denied having a fever. Past medical history was significant only for systemic arterial hypertension. There was no history of diabetes mellitus or other comorbidities. She did not drink alcohol. Physical examination revealed mild neck stiffness and a nonfocal neurological examination. Funduscopy findings were normal. The patient had no lymphadenopathy, fever, or skin alterations. An emergency cranial computed tomographic scan showed discrete sulcus obliteration (Figure 1, left). Magnetic resonance imaging (MRI) showed hyperintensity in the frontal, temporal, and occipital lobes (Figure 1, right).
Chang HJ, Zuccotti G. Frontal Headache. JAMA. 2011;306(3):317-318. doi:10.1001/jama.2011.994