Author Affiliations: Department of Family Medicine, University of Miami School of Medicine, Miami, Florida; Florida State University, Tallahassee; and Florida International University, Miami (email@example.com).
Alcohol and tobacco are the most common causes of substance abuse and dependence worldwide. In the United States, excessive alcohol consumption is associated with approximately 75 000 deaths per year and is a factor in approximately 41% of all deaths from motor vehicle crashes.1 More deaths are caused each year in the United States by tobacco use than by human immunodeficiency virus, illegal drug use, alcohol use, motor vehicle injuries, suicides, and murders combined.2 Alcohol consumption and tobacco use are closely linked behaviors; therefore, the concurrent use of alcohol and tobacco is of particular concern given the adverse combined health consequences and significant adverse economic effects of this drug combination on the individual and on society.
Wollschlaeger B. Alcohol and Tobacco: Medical and Sociological Aspects of Use, Abuse and Addiction. JAMA. 2011;306(4):440-441. doi:10.1001/jama.2011.1050