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July 27, 2011

Clinical Inertia and Uncertainty in Medicine

Author Affiliations

Author Affiliations: Emory University School of Medicine, Atlanta, Georgia (

JAMA. 2011;306(4):383-384. doi:10.1001/jama.2011.1044

To the Editor: Drs Giugliano and Esposito1 suggested that lowering risk factor levels is not always better. Clinical inertia may benefit patients, such as failing to intensify antihypertensive therapy in patients with a history of orthostasis. However, we question the extent of their assertions and believe that clinical inertia remains an important problem worth solving.

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