Author Affiliations: Department of Anesthesiology and Intensive Care Medicine, Tübingen University Hospital, Tübingen, Germany (Drs König and Rosenberger) (email@example.com); and Department of Anesthesiology, Perioperative and Pain Medicine, Harvard Medical School, Boston, Massachusetts (Dr Mirakaj).
To the Editor: The study by Dr Rice and colleagues investigated the effect of enteral n-3 fatty acids, GLA, and antioxidants on ALI.1 The authors demonstrated that patients in the treatment group had a higher mortality rate and fewer days free from the ventilator, intensive care unit, and organ failure compared with the control group. These results are in contrast to previous studies demonstrating a protective role for n-3 fatty acids during sepsis or acute respiratory distress syndrome.2
König K, Rosenberger P, Mirakaj V. Supplementation in Acute Lung Injury. JAMA. 2012;307(2):144-146. doi:10.1001/jama.2011.1984