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Article
February 1, 1908

THE ANTIMICROBIC ACTION OF BROMIN.

Author Affiliations

Senn Fellow in Surgery, Rush Medical College, in Affiliation with the University of Chicago; Assistant Instructor in Skin and Venereal Diseases, Chicago Policlinic. CHICAGO.

JAMA. 1908;L(5):345-351. doi:10.1001/jama.1908.25310310021001e
Abstract

PREFACE.  The marked potency of iodin as a germicide in a comparatively weak solution as shown experimentally by myself1 and clinically by Prof. N. Senn, for several years both previous and subsequent to these experiments, raised the question whether another member of the halogen group would prove of equal or superior value, considered from the same standpoint. For the purpose of determining this question Dr. Senn requested that bromin be made the subject of a similarly conducted research. A review of the more common antiseptics has been incorporated in my previous article and will, therefore, be omitted here.

EXPERIMENTAL TECHNIC. 

(A) Method of Preparation of Bromin Solution.  -An aqueous solution of bromin was employed, using as the mother solution one equal to 1 per cent. Since bromin is a heavy liquid, this solution was made by volume after the following formula:In order to get this amount of bromin

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