The FDA has created a Web site for clinical investigators (http://www.fda.gov/cder/about/smallbiz/clinical_investigator.htm) with information including, among other things, investigators' regulatory responsibilities (especially for the protection of human subjects), FDA rules, and procedures of institutional review boards.
Henney JE. Web Site for Clinical Investigators. JAMA. 2000;283(21):2779. doi:10.1001/jama.283.21.2779