[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.146.179.146. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
July 17, 1897

ANTITOXIC SERUM FOR TUBERCULOSIS.

Author Affiliations

DIRECTOR, BIOCHEMIC LABORATORY, BUREAU OF ANIMAL INDUSTRY, DEPARTMENT OF AGRICULTURE, WASHINGTON, D. C.

JAMA. 1897;XXIX(3):113-115. doi:10.1001/jama.1897.02440290019001h
Abstract

In speaking briefly of the preparation and use of antitoxic serums in my laboratory, it may be of interest to note a few points which indicated the advisability of the method I have used for treating animals to produce the desired serum.

The preliminary experiments, published in 18941 on the production of an immunity or resistance to tuberculosis by attenuated cultures, have been continued and are confirmatory of the first results, showing the production of great resistance and in some cases complete immunity. A detail of two sets of these experiments may be given as an instance of their general results.

The first effect of the injection of the attenuated germ was, in some instances, to cause a slight decrease in weight; sometimes a local swelling was noted at the point of injection, and occasionally an enlargement of the inguinal glands. This disappeared after some weeks. This local swelling is

First Page Preview View Large
First page PDF preview
First page PDF preview
×