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April 4, 2012

The Challenge of Individualizing Treatments for Patients With Breast Cancer

Author Affiliations

Author Affiliations: Departments of Medicine and Health Management & Policy, University of Michigan, Ann Arbor (Dr Katz); and Department of Clinical Oncology, Memorial Sloan-Kettering Cancer Center, and Weill Medical College of Cornell University (Dr Morrow), New York, New York.

JAMA. 2012;307(13):1379-1380. doi:10.1001/jama.2012.409

One of the most complex challenges clinicians and their patients with breast cancer face is to determine a treatment plan for disease with relatively favorable prognosis. Advances in treatment have improved life expectancy, but these advances have come at a steep price because treatments impose substantial morbidity and burden on patients and their families. Concerns about the potential harm of treatments have increased as population-based screening has identified an increased number of breast cancer patients with relatively favorable prognosis.1 These concerns have motivated several initiatives to reduce morbidity and treatment burden.

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