Author Affiliations: Department of Cardiology, University of Athens Medical School, Athens, Greece (email@example.com).
To the Editor: The article by Dr Holmes and colleagues1 appraised the evidence on the association between CYP2C19 genotype and clopidogrel response through a systematic review and meta-analysis. Their results showed that although there was an association between the CYP2C19 genotype and clopidogrel responsiveness, overall there was no significant association of genotype with cardiovascular events.
Siasos G, Tousoulis D, Stefanadis C. CYP2C19 Genotype and Cardiovascular Events. JAMA. 2012;307(14):1482-1485. doi:10.1001/jama.2012.445