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Medical News and Perspectives
January 23, 2008

Lessening of Cell Stiffness Might Serve as New Biomarker for Malignancy

JAMA. 2008;299(3):276. doi:10.1001/jama.299.3.276

A patient's cancer cells are nearly 4 times softer than similar but normal neighboring cells, according to recent research. The findings suggest that a “mechanical signature” might be a new biomarker of malignancy and could aid in the diagnosis, and even treatment, of cancer (Cross SE et al. Nature Nanotechnology. 10.1038/nnano.2007.388 [published online December 2, 2007]).

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