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Medical News and Perspectives
January 9/16, 2008

Scientists Build Map of Imprinted Genes

JAMA. 2008;299(2):161. doi:10.1001/jama.2007.62

While imprinted genes have been linked to a variety of diseases, until now only several dozen have been identified. But a new report reveals a map of 156 new likely imprinted genes scattered throughout the human genome (Luedi PP et al. Genome Res. 2007;17[12]:1723-1730).

Unlike the majority of genes—in which both the maternally and paternally inherited copies are active—in imprinted genes, one of these copies is silenced.

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