In a Clinical Crossroads article published in October 2008,1 James Ellison, MD, MPH, discussed the clinical assessment and management of memory difficulties. The patient, Ms E, a 60-year-old woman with a diagnosis of mild cognitive impairment (MCI), described her health as good until the summer of 2005. Evaluation was performed by her primary care practitioner, who prescribed paroxetine, 30 mg/d, for depressive symptoms. Her magnetic resonance imaging scan showed subcortical and periventricular white matter lesions with no significant cortical atrophy.
Libman H, Trivedi NS. Update: A 60-Year-Old Woman With Mild Memory ImpairmentReview of Mild Cognitive Impairment. JAMA. 2012;307(17):1858. doi:10.1001/jama.2012.3464