[Skip to Content]
[Skip to Content Landing]
Citations 0
Lab Reports
October 3, 2007

Healthy Obese Mice

JAMA. 2007;298(13):1506. doi:10.1001/jama.298.13.1506-a

A novel model of morbid obesity associated with an improved metabolic profile may help explain why not all obese people are diabetic, according to a study led by scientists at the University of Texas Southwestern Medical Center, in Dallas (Kim JY et al. J Clin Invest. doi:10.1172/jci31021 [published online ahead of print August 23, 2007]). The study found that obese mice with an abundance of the hormone adiponectin and a lack of another hormone, leptin, do not develop insulin resistance. While adiponectin controls sensitivity to insulin, leptin curbs appetite.

First Page Preview View Large
First page PDF preview
First page PDF preview