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Lab Reports
October 3, 2007

Stem Cells for Heart Health

JAMA. 2007;298(13):1506. doi:10.1001/jama.298.13.1506-d

Cardiac muscle cells derived from human embryonic stem cells might help repair damage from myocardial infarction, according to a study led by scientists at the University of Washington, in Seattle (Laflamme MA et al. Nat Biotechnol. doi:10.1038/nbt1327 [published online August 26, 2007]).

The investigators found that transplantation of cardiomyocytes generated from human embryonic stem cells improved the cardiac function of rats subjected to experimental myocardial infarction. Specifically, the engrafted cells attenuated ventricular dilation and preserved contractile function compared with control rats receiving noncardiac human embryonic stem cells.

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