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Books, Journals, New Media
May 20, 1998

Internal Medicine

Author Affiliations

Margaret A.WinkerMD, Senior EditorIndividualAuthorPhil B.FontanarosaMD, Senior EditorIndividualAuthor

JAMA. 1998;279(19):1527-1528. doi:10-1001/pubs.JAMA-ISSN-0098-7484-279-19-jbk0520

In Reply.—Our study examined essentially all available information on cancer rates in the United States relevant to the periods before, during, and after the widespread exposure of infants and children to SV40 through contaminated poliovirus vaccine (1955-1963). Incidence data were obtained from the SEER program, the principal source of cancer statistics for the nation, which began in 1973. Thus, for the birth cohorts injected with contaminated vaccine, surveillance had not started until these individuals were at least 10 years of age. To examine rates of cancer at younger ages, we studied national mortality statistics as well as incidence data from the Connecticut Tumor Registry, the only population-based cancer registry in the country that was well established at the time of the event.

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