Margaret A.WinkerMD, Senior EditorIndividualAuthorPhil B.FontanarosaMD, Senior EditorIndividualAuthor
To the Editor.— In the article by Dr
Meehan and colleagues,1 the Figure (on page
2083) shows a relationship between the hours within which antibiotics were
administered and the adjusted odds of 30-day mortality.
I am unable to reconcile the Figure with the conclusion that administering
antibiotics within 8 hours of hospital arrival is associated with improved
survival. The shortest interval of 1 hour is associated with the highest mortality,
and the time frame after 8 hours is associated with the lowest odds ratio.
Unless I am misinterpreting the figure, the conclusion of the article is erroneous,
even though plausible.
Hoffman MF. Quality of Care for Elderly Patients With Pneumonia. JAMA. 1998;279(24):1950-1952. doi:10-1001/pubs.JAMA-ISSN-0098-7484-279-24-jac80011