Margaret A.WinkerMDIndividualAuthorPhil B.FontanarosaMD, Senior EditorIndividualAuthor
To the Editor.—That there is a connection between folic acid, pyridoxine (vitamin B6), homocysteine, and heart disease in women seems to be well established on the basis of multiple studies.1- 3 Of concern, however, is the reluctance by researchers to mention the established association between use of oral contraceptives and deficiency of folate, B vitamins, and other nutrients.
Littell JT. Relationship of Dietary Folate and Vitamin B6 With Coronary Heart Disease in Women. JAMA. 1998;280(5):417-419. doi:10-1001/pubs.JAMA-ISSN-0098-7484-280-5-jbk0805