Margaret A.WinkerMD, Senior EditorIndividualAuthorPhil B.FontanarosaMD, Senior EditorIndividualAuthor
In Reply.—The suggestion of Drs Messerli and Grossman that concomitant diuretic use may account for the association of renal cell cancer with the use of calcium channel blockers, angiotensin-converting enzyme inhibitors, and β-blockers is plausible. However, it has been difficult to assess the separate effects of diuretics and antihypertensive drugs because they are so often used together.
Rosenberg L. Antihypertensive Agents and the Risk of Cancer—Reply. JAMA. 1998;280(7):600. doi:10-1001/pubs.JAMA-ISSN-0098-7484-280-7-jbk0819-g