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August 19, 1998

Antihypertensive Agents and the Risk of Cancer—Reply

Author Affiliations

Margaret A.WinkerMD, Senior EditorIndividualAuthorPhil B.FontanarosaMD, Senior EditorIndividualAuthor

JAMA. 1998;280(7):600. doi:10-1001/pubs.JAMA-ISSN-0098-7484-280-7-jbk0819-g

In Reply.—The suggestion of Drs Messerli and Grossman that concomitant diuretic use may account for the association of renal cell cancer with the use of calcium channel blockers, angiotensin-converting enzyme inhibitors, and β-blockers is plausible. However, it has been difficult to assess the separate effects of diuretics and antihypertensive drugs because they are so often used together.

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