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December 9, 1998

The Changing Treatment Paradigm for Acute Otitis Media

Author Affiliations

Margaret A.WinkerMD, Senior EditorIndividualAuthorPhil B.FontanarosaMD, Senior EditorIndividualAuthor

JAMA. 1998;280(22):1903-1904. doi:10.1001/jama.280.22.1903

To the Editor.—The meta-analysis by Ms Kozyrskyj and colleagues1 provides clear and compelling evidence that the standard practice in the United States of 10 days of antibiotic therapy in the treatment of childhood acute otitis media (AOM) is not evidence-based medicine and is perhaps a dangerous clinical practice. This meta-analysis reinforces last year's extensive review by Pichichero and Cohen2 that reached the same conclusions.

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