Margaret A.WinkerMD, Senior EditorIndividualAuthorPhil B.FontanarosaMD, Senior EditorIndividualAuthor
In Reply.— In response to both the critical
and sympathetic letter authors, our main concern is that there seems to be
some discrepancy between the prevalent discourse of what quality-of-life and
HRQL instruments are supposed to measure and what they actually do measure.
In our technical jargon, we would say that there is a content validity issue
(ie, most so-called quality-of-life instruments do not measure quality of
life but health status instead). We think that such a situation should be
dealt with seriously, since stating that the outcome of a given medical intervention
is an improvement in the quality of life of the recipients may raise undue
expectations among the patients, the medical community, the public, or the
regulatory authorities. Therefore, we believe our responsibility is to address
this problem publicly and call for a much needed debate.
Leplége A, Hunt S. Defining and Measuring Quality of Life in Medicine—Reply. JAMA. 1998;279(6):429-431. doi:10-1001/pubs.JAMA-ISSN-0098-7484-279-6-jac81007