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March 14, 2012

Intracoronary Bone Marrow Mononuclear Cells After Myocardial Infarction

Author Affiliations

Author Affiliation: Interventional Cardiology Division, Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada (

JAMA. 2012;307(10):1022-1024. doi:10.1001/jama.2012.278

To the Editor: The LateTIME trial findings1 suggest a lack of benefit from intracoronary delivery of bone marrow mononuclear cells (BMCs) 2 to 3 weeks after primary percutaneous coronary intervention (PCI) in patients with myocardial infarction (MI) and depressed left ventricular (LV) function. However, further clarification is needed to better appreciate the study conclusions.

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