A multi-institution team of researchers has discovered that the primary gene linked to the development of schizophrenia controls the birth of new neurons in developing and adult mouse brains.
Variants in a gene called disrupted in schizophrenia 1 (DISC 1) have been linked to the development of schizophrenia and other mental disorders in humans. The gene was previously known to play a key role in the integration of new neurons into the circuits of the brain.
Kuehn BM. Schizophrenia Biology. JAMA. 2009;301(17):1758. doi:10.1001/jama.2009.567