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October 31, 1931


JAMA. 1931;97(18):1315-1316. doi:10.1001/jama.1931.02730180051021

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Early Diagnosis of Cancer of the Cervix Uteri  At the second Frauenklinik of the University of Vienna, a method has been used during the last eighteen months which makes it possible to recognize in the earliest stages one of the most frequent forms of cancer of the uterus. The portio is brought into view with the aid of a speculum and is painted with an aqueous solution of iodine. The normal mucous membrane is colored a deep brown in a few seconds, but if there is a cancerous area it remains colorless and thus forms a distinct contrast with the surrounding healthy tissues. With the aid of a magnifying apparatus introduced with the speculum, the tiniest spots awakening a suspicion of cancer by reason of their colorless appearance can be discovered. With a curet some of the tissues comprising the colorless spots are removed and examined microscopically. This diagnostic method

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