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In this booklet the authors review the diagnosis, pathologic changes and roentgen observations in pulmonary syphilis. They report twelve cases of their own, with excellent roentgenograms of the lungs. The diagnosis of pulmonary syphilis is difficult and can be confirmed only by the postmortem demonstration of the interstitial or gummatous lesions. Even the pathologist must be careful about making the diagnosis. There is no definite symptom complex for pulmonary syphilis, with its variety of forms. The disease may closely simulate other chronic diseases, such as tuberculosis, actinomycosis, bronchiectasis, lymphogranuloma, and carcinoma of a bronchus. The great uncertainty and difficulty in the diagnosis of pulmonary syphilis, both clinically as well as post mortem, justify one in being skeptical about many of the cases of tertiary pulmonary syphilis reported in the literature. Clinically, pulmonary syphilis is not to be diagnosed with certainty. The cases in which a cure has been effected do
Die Lungensyphilis des Erwachsenen.. JAMA. 1931;97(21):1561. doi:10.1001/jama.1931.02730210059041