December 19, 1931


Author Affiliations


From the Department of Neurology of Washington University and the Barnes Hospital.

JAMA. 1931;97(25):1850-1852. doi:10.1001/jama.1931.02730250008003

Hypoglycemia as the cause of a variety of neurologic pictures has been most forcefully brought to attention during the past year by the coincidence of several similar cases which appeared in Barnes Hospital. One of these, which was referred to us with a previous diagnosis of epilepsy, was found to show a classic picture of hypoglycemia caused by an adenoma of the pancreas.1 It was possible to demonstrate and remove the adenoma, with the disappearance of hypoglycemia and the clinical cure of the patient. A patient of Womack, Gnagi and Graham,2 in whom an adenoma of the pancreas was demonstrated, had had periods of confusion and convulsive movements for over a year, had been placed on phenobarbital and considered as a brain tumor suspect. Another case,3 diagnosed as syphilis of the nervous system, terminated fatally in convulsions. At autopsy a small adenoma of the pancreas was found.

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