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January 9, 1932


Author Affiliations

San Francisco. Professor of Tropical Medicine, University of California

JAMA. 1932;98(2):162. doi:10.1001/jama.1932.02730280070029

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To the Editor:  —In Queries and Minor Notes (The Journal, Dec. 19, 1931, p. 1913) is a query and reply under the heading "Ulcerative Colitis—Endamoeba Histolytica." I wish to draw attention to two things in connection with this query. In the first place, the query itself shows that adequate diagnosis of amebiasis had not been made. Without ironhematoxylin stains, identification of the ameba is most uncertain. In the second place the answer contains many points which are not well authenticated. Taking these in order, eosinophilia is not characteristic of amebiasis and, when present, can usually be ascribed to some other factor. In fact, the blood count is absolutely useless in the diagnosis of amebiasis. It is certainly not true that if colon lesions are due to Endamoeba histolytica a proctoscopic study should reveal typical ulcers. It is not uncommon to find the lower bowel free of amebic lesions when the

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