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This classic monograph, the first edition of which was published in 1919, has never enjoyed the general attention from all fields of medical science that it justly deserves. Perhaps this is because of the unassuming title of the work, which for some carries a flavor of the "muscle-twitching days" spent in the laboratory. The salient feature of the book is its integration of all the processes that are associated with exercise. The metabolism of muscle is allocated its proper place as a small part of the general picture. The respiratory exchange, the control of respiration, the behavior of the heart and of the vascular system, diet and the effects of altitude are some of the topics comprehensively treated, with particular attention being paid to the correlation of the changes occurring during exercise. The importance to the practitioner of an understanding of the physiology of exercise in this broad sense is
The Physiology of Muscular Exercise.. JAMA. 1932;98(2):167. doi:10.1001/jama.1932.02730280075039