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July 13, 1935


JAMA. 1935;105(2):113-114. doi:10.1001/jama.1935.92760280004010

Note.—  This article and the articles in the previous issues of The Journal are part of a series published under the auspices of the Council on Pharmacy and Chemistry. Other articles will appear in succeeding issues. When completed, the series will be published in book form.—Ed.The parathyroid glands are concerned with calcium-phosphorus metabolism. Experimental work with animals indicates that calcium-phosphorus metabolism is of great importance in the body because it is necessary to the calcification of bone and teeth. The ionic calcium of the blood serum serves to control the varying normal degrees of irritability of nerve and of voluntary, as well as of involuntary, muscle. Because of this effect on the nerve endings and the involuntary muscle, it also increases vascular tone. It plays an important rôle in the clotting of blood and milk. That portion of the nonionized calcium which is diffusible may play its part with the

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