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July 27, 1935


JAMA. 1935;105(4):270-274. doi:10.1001/jama.1935.92760300002008

Note.—  This article and the articles in the previous issues ofThe Journalare part of a series published under the auspices of the Council on Pharmacy and Chemistry. Other articles will appear in succeeding issues. When completed, the series will be published in book form.—Ed.The time-honored and productive physiologic methods of studying the function of an organ are (1) to remove it completely or in part and to observe the abnormal effects attributable to its absence, and (2) to make extracts of the tissue in various ways and to study the mechanism of action of the fractions that are found to possess specific physiologic potency. The pancreas has lent itself admirably to this procedure in the case of both internal and external secretions. Since this article is, in large part, a preface to a consideration of the therapeutics of pancreatic

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